Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4030013 | 1.00 | LMNA (0.46) | LMNADNM1TSHRTHRBPLA2G1B | |
| SCHEMBL10528718 | 1.00 | LMNA (0.46) | LMNADNM1TSHRTHRBPLA2G1B | |
| SCHEMBL27869627 | 1.00 | LMNA (0.46) | LMNADNM1TSHRTHRBPLA2G1B | |
| SCHEMBL6155980 | 1.00 | LMNA (0.46) | LMNADNM1TSHRTHRBPLA2G1B | |
| SCHEMBL4098039 | 0.97 | LMNA (0.42) | LMNADNM1TSHRTHRBPLA2G1B | |
| SCHEMBL27605329 | 0.90 | — | — | |
| SCHEMBL27611845 | 0.78 | — | — | |
| SCHEMBL27587383 | 0.78 | LMNA (0.44) | LMNADNM1TSHRTHRBPLA2G1B | |
| SCHEMBL8824517 | 0.76 | TSHR (0.47) | LMNADNM1TSHRTHRBPLA2G1B | |
| SCHEMBL8746175 | 0.76 | TSHR (0.47) | LMNADNM1TSHRTHRBPLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2464708-A1 | HYDROPHOBICALLY AND CATIONICALLY MODIFIED RELATIVE PERMEABILITY MODIFIERS AND ASSOCIATED METHODS | Halliburton Energy Services, Inc. (US) | 2012-06-20 | — | — | EP | disclosed |
| WO-2011018604-A1 | HYDROPHOBICALLY AND CATIONICALLY MODIFIED RELATIVE PERMEABILITY MODIFIERS AND ASSOCIATED METHODS | HAAIBURTON ENERGY SERVICES, INC. (US) | 2011-02-17 | — | — | WO | disclosed |