Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | FBP1 | P09467 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11638083 | 0.87 | ALDH1A1 (0.51) | ALDH1A1CYP2C9TDP1LMNATSHR | |
| SCHEMBL11527984 | 0.86 | GAA (0.47) | ALDH1A1TDP1TSHRCYP2C19POLB | |
| SCHEMBL11632341 | 0.83 | POLB (0.42) | ALDH1A1TDP1TSHRMAPTCYP2C19 | |
| SCHEMBL11634252 | 0.81 | SMN1; SMN2 (0.42) | TDP1TSHRMAPTCYP2C19POLB | |
| SCHEMBL11595726 | 0.81 | F10 (0.46) | ALDH1A1TDP1TSHRCYP2C19POLB | |
| SCHEMBL11632049 | 0.80 | POLB (0.44) | TDP1TSHRMAPTCYP2C19POLB | |
| SCHEMBL11630310 | 0.78 | SMN1; SMN2 (0.45) | ALDH1A1CYP2C9TDP1TSHRMAPT | |
| SCHEMBL11633823 | 0.78 | SMN1; SMN2 (0.41) | ALDH1A1CYP2C9TSHRMAPTCYP2C19 | |
| SCHEMBL11529122 | 0.78 | POLB (0.45) | ALDH1A1TDP1TSHRMAPTCYP2C19 | |
| SCHEMBL11631131 | 0.78 | ALDH1A1 (0.46) | ALDH1A1LMNATSHRMAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4083979-A | Thiazolidine derivatives and their use as salidiuretics | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-04-11 | — | — | US | disclosed |