Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SLCO2A1 | Q92959 | 2/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.33 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11780570 | 1.00 | PTGFR (0.35) | PTGFRALDH1A1TBXA2RLMNASLCO2A1 | |
| SCHEMBL11632080 | 0.91 | ALDH1A1 (0.35) | PTGFRALDH1A1TBXA2RLMNAHPGD | |
| SCHEMBL11635837 | 0.91 | ALDH1A1 (0.35) | PTGFRALDH1A1TBXA2RLMNAHPGD | |
| SCHEMBL11652695 | 0.91 | PTGFR (0.30) | PTGFR | |
| SCHEMBL11651681 | 0.91 | — | — | |
| SCHEMBL11844308 | 0.90 | TBXA2R (0.33) | PTGFRTBXA2R | |
| SCHEMBL11841851 | 0.90 | TBXA2R (0.33) | PTGFRTBXA2R | |
| SCHEMBL11778033 | 0.90 | — | — | |
| SCHEMBL11759785 | 0.89 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL11840472 | 0.88 | PDE4D (0.33) | TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4110341-A | Dithio prostaglandin derivatives | ONO PHARMACEUTICAL COMPANY (JP) | 1978-08-29 | — | — | US | disclosed |
| US-3997587-A | D1- and 8R-9-fluoro-prostadienoic acid derivatives | SYNTEX (U.S.A.) INC. (US) | 1976-12-14 | — | — | US | disclosed |
| US-3989736-A | INCREASED DURATION OF ACTION | PFIZER INC. (US) | 1976-11-02 | — | — | US | disclosed |