SCHEMBL11633482

SCHEMBL11633482

Clc1cc(Cl)cc(C2OCC(OCc3ccccc3)CO2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSL P07711 1/20 0.39
CTSB P07858 1/20 0.39
CTSK P43235 1/20 0.39
OPRM1 P35372 2/20 0.36
OPRL1 P41146 2/20 0.36
DPP4 P27487 1/20 0.36
SLC6A4 P31645 2/20 0.36
TACR1 P25103 1/20 0.36
TMEM97 Q5BJF2 1/20 0.35
CARM1 Q86X55 1/20 0.35
PRMT6 Q96LA8 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
PRMT8 Q9NR22 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35
BCHE P06276 2/20 0.34
GRIN1 Q05586 1/20 0.34
GRIN2B Q13224 1/20 0.34
CYP2C19 P33261 1/20 0.34
KDM1A O60341 1/20 0.34
NAAA Q02083 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11633476 1.00 CTSL (0.39) CTSLCTSBCTSKOPRM1OPRL1
SCHEMBL11632585 0.89 BCHE (0.40) CTSLCTSBCTSKSLC6A4TACR1
SCHEMBL11632580 0.89 BCHE (0.40) CTSLCTSBCTSKSLC6A4TACR1
SCHEMBL11633685 0.87 KCNA5 (0.40) CTSLCTSBCTSKOPRM1OPRL1
SCHEMBL11633688 0.87 KCNA5 (0.40) CTSLCTSBCTSKOPRM1OPRL1
SCHEMBL1560842 0.85 CTSL (0.45) CTSLCTSBCTSKOPRM1OPRL1
SCHEMBL11637675 0.85 CTSL (0.45) CTSLCTSBCTSKOPRM1OPRL1
SCHEMBL11635684 0.85 CTSL (0.45) CTSLCTSBCTSKOPRM1OPRL1
SCHEMBL11634473 0.84 MEN1 (0.42) CTSLCTSBCTSKTACR1CARM1
SCHEMBL11634478 0.84 MEN1 (0.42) CTSLCTSBCTSKTACR1CARM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4077982-A HERBICIDES FMC CORPORATION (US) 1978-03-07 US disclosed