Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10626360 | 0.90 | CHEK1 (0.79) | CHEK1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL14199812 | 0.86 | CHEK1 (0.84) | CHEK1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL11636020 | 0.83 | CHEK1 (0.68) | CHEK1KMT2AMEN1L3MBTL1 | |
| SCHEMBL11629994 | 0.83 | CHEK1 (0.69) | CHEK1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL10625641 | 0.83 | CHEK1 (0.69) | CHEK1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL1152020 | 0.82 | CHEK1 (1.00) | CHEK1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL11667243 | 0.81 | CHEK1 (0.97) | CHEK1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL11638195 | 0.80 | CHEK1 (0.64) | CHEK1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL10622272 | 0.80 | CHEK1 (0.64) | CHEK1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL11634853 | 0.80 | CHEK1 (0.64) | CHEK1KMT2AMEN1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4103015-A | TRICYCLIC THIOXANTHONE-10,10-DIOXIDES | BURROUGHS WELLCOME CO. (US) | 1978-07-25 | — | — | US | disclosed |