Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11635945 | 0.89 | TSHR (0.54) | TSHRHTR2AHTR2CHTR2BTRPM4 | |
| SCHEMBL11809571 | 0.87 | SMN1; SMN2 (0.40) | TSHRHTR2AHTR2CHTR2BLMNA | |
| SCHEMBL11808874 | 0.84 | POLB (0.47) | LMNASMN1; SMN2NPSR1NPC1RAB9A | |
| SCHEMBL11823419 | 0.81 | MEN1 (0.40) | TSHRLMNAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL11837009 | 0.81 | TSHR (0.57) | TSHRHTR2AHTR2CHTR2BTRPM4 | |
| SCHEMBL11513946 | 0.80 | TSHR (0.56) | TSHRHTR2AHTR2CHTR2BTRPM4 | |
| SCHEMBL11825343 | 0.79 | CYP2C9 (0.47) | TSHRHTR2BLMNAMAPTSMN1; SMN2 | |
| SCHEMBL11806845 | 0.78 | PPARA (0.50) | MAPTCYP1A2MEN1KMT2ASLC6A2 | |
| SCHEMBL11634328 | 0.78 | POLB (0.50) | TSHRHTR2AHTR2CHTR2BLMNA | |
| SCHEMBL11803263 | 0.77 | OGG1 (0.47) | MAPTNPC1RAB9AKDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4079142-A | 1-Propyl-triazolyl antimycotic compositions and methods of treating mycoses | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-14 | — | — | US | disclosed |
| US-3993765-A | ANTIMUCOTICS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |
| US-3972892-A | FUNGICIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-03 | — | — | US | disclosed |