Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.66 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.66 |
| ▸ | RELA | Q04206 | 1/20 | 0.66 |
| ▸ | PDE4A | P27815 | 1/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.60 |
| ▸ | ERN1 | O75460 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19475516 | 0.84 | ADORA2A (0.56) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| SCHEMBL30820503 | 0.84 | ADORA2A (0.56) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| SCHEMBL29208511 | 0.82 | MEN1 (0.56) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| SCHEMBL8844119 | 0.82 | KDM4E (0.67) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| SCHEMBL2389780 | 0.81 | ERN1 (0.57) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| SCHEMBL2388588 | 0.81 | MAPT (0.64) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| SCHEMBL4054502 | 0.81 | NPC1 (0.64) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| SCHEMBL4036698 | 0.80 | ERN1 (0.68) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| SCHEMBL1307991 | 0.80 | TUBB4A (0.55) | MEN1KMT2AMAPK1SMN1; SMN2TP53 | |
| SCHEMBL2389984 | 0.80 | ERN1 (0.56) | MEN1KMT2AMAPK1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103052640-B | Furopyridine Derivatives | 默克专利股份公司 | 2017-06-30 | — | — | CN | disclosed |
| CN-102171173-B | Scalable synthetic process for making meso-1,4 - bis (3,4 - dimethoxyphenyl)-dimethyl butane | ERIMOS PHARMACEUTICALS LLC | 2015-05-13 | — | — | CN | disclosed |
| US-4108997-A | Diuretic [2]benzopyrano[4,3-b]pyridines and process therefor | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1978-08-22 | — | — | US | disclosed |