Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CBX7 | O95931 | 2/20 | 0.42 |
| ▸ | CDYL2 | Q8N8U2 | 2/20 | 0.42 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.42 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29043141 | 0.82 | TSHR (0.55) | TSHRMEN1KMT2AL3MBTL1CYP2C9 | |
| SCHEMBL7832589 | 0.77 | SLC6A2 (0.51) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL1177318 | 0.75 | CYP1A2 (0.62) | SLC6A2SLC6A3MEN1KMT2ASLC6A4 | |
| SCHEMBL15790781 | 0.74 | TSHR (0.56) | TSHRMEN1KMT2AL3MBTL1CYP2C9 | |
| Maleic Acid SCHEMBL9615196 | 0.74 | SLC6A2 (0.45) | SLC6A2SLC6A3MEN1KMT2ASLC6A4 | |
| Fumaric Acid SCHEMBL9615197 | 0.74 | SLC6A2 (0.45) | SLC6A2SLC6A3MEN1KMT2ASLC6A4 | |
| SCHEMBL11679858 | 0.74 | SLC6A2 (0.51) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL11677994 | 0.72 | SLC6A2 (0.49) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL28112902 | 0.71 | SLC6A2 (0.44) | SLC6A2SLC6A3SLC6A4CYP2C9CYP2C19 | |
| SCHEMBL474614 | 0.70 | TSHR (0.60) | TSHRMEN1KMT2AL3MBTL1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4079135-A | Morpholine derivatives as antidepressants | IMPERIAL CHEMICAL INDUSTRIES LIMITED (EN) | 1978-03-14 | — | — | US | disclosed |
| US-4033951-A | ANTIDEPRESSANTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (EN) | 1977-07-05 | — | — | US | disclosed |
| US-3989699-A | ANTIDEPRESSANTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (EN) | 1976-11-02 | — | — | US | disclosed |