Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 15/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11681069 | 0.89 | SLC6A2 (0.46) | SLC6A2SLC6A3SLC6A4HTR2BHTR2A | |
| SCHEMBL11679389 | 0.87 | SLC6A2 (0.42) | SLC6A2SLC6A3SLC6A4HTR2BHTR2A | |
| SCHEMBL11679397 | 0.87 | GRIN1 (0.44) | SLC6A2SLC6A3SLC6A4HTR2BHTR2A | |
| SCHEMBL11678040 | 0.86 | SLC6A2 (0.48) | SLC6A2SLC6A3SLC6A4HTR2BHTR2A | |
| Maleic Acid SCHEMBL9615196 | 0.83 | SLC6A2 (0.45) | SLC6A2SLC6A3SLC6A4 | |
| Fumaric Acid SCHEMBL9615197 | 0.83 | SLC6A2 (0.45) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL11679858 | 0.83 | SLC6A2 (0.51) | SLC6A2SLC6A3SLC6A4HTR2BHTR2A | |
| SCHEMBL11677994 | 0.81 | SLC6A2 (0.49) | SLC6A2SLC6A3SLC6A4HTR2BHTR2A | |
| SCHEMBL7167351 | 0.78 | HTR2A (0.47) | SLC6A2SLC6A3SLC6A4HTR2BHTR2A | |
| SCHEMBL14707008 | 0.78 | HTR2A (0.47) | SLC6A2SLC6A3SLC6A4HTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214816-B1 | ANTIDIABETIC AGENTS, ANALGESICS AND ANTIINFLAMMATORY AGENTS | NOVO NORDISK A/S (DK) | 2001-04-10 | — | — | US | disclosed |
| EP-1071679-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999047517-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-09-23 | — | — | WO | disclosed |
| US-4017621-A | 2-Morpholinyl tricyclic dibenzazepine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-04-12 | — | — | US | disclosed |