Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM6A | O15550 | 1/20 | 0.41 |
| ▸ | FASN | P49327 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11634742 | 0.82 | PTGS2 (0.50) | NPC1RAB9APTGS2MAPTKMT2A | |
| SCHEMBL11809886 | 0.81 | NPC1 (0.70) | NPC1RAB9AMAPTKMT2AKDM4E | |
| SCHEMBL11809710 | 0.80 | NPC1 (0.68) | NPC1RAB9AMAPTKMT2AKDM4E | |
| SCHEMBL11807169 | 0.79 | NPC1 (0.57) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL977466 | 0.75 | NPC1 (0.69) | NPC1RAB9AMAPTKMT2AKDM4E | |
| Benzoic Acid SCHEMBL11551976 | 0.74 | NPC1 (0.68) | NPC1RAB9AMAPTKMT2AKDM4E | |
| SCHEMBL10415956 | 0.73 | HPSE (0.57) | NPC1RAB9AMAPTKMT2AKDM4E | |
| SCHEMBL12171404 | 0.73 | NPC1 (0.73) | NPC1RAB9AMAPTKMT2AKDM4E | |
| SCHEMBL17265011 | 0.73 | KDM6B (0.60) | NPC1RAB9APTGS2MAPTKMT2A | |
| SCHEMBL3317791 | 0.73 | KDM6B (0.63) | NPC1RAB9APTGS2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4105631-A | MULTICHROMOPHORIC ULTRAVIOLET STABILIZERS AND THEIR USE IN ORGANIC COMPOSITIONS | EASTMAN KODAK COMPANY (US) | 1978-08-08 | — | — | US | disclosed |
| US-4043973-A | PIGMENTS, COLORANTS, FILLERS, REINFORCING AGENTS | EASTMAN KODAK COMPANY (US) | 1977-08-23 | — | — | US | disclosed |
| US-3936419-A | Multichromophoric ultraviolet stabilizers and their use in organic compositions | EASTMAN KODAK COMPANY (US) | 1976-02-03 | — | — | US | disclosed |