Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 8/20 | 0.52 |
| ▸ | ATG4B | Q9Y4P1 | 3/20 | 0.37 |
| ▸ | TGM2 | P21980 | 2/20 | 0.36 |
| ▸ | PPOX | P50336 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 3/20 | 0.34 |
| ▸ | CDK2 | P24941 | 3/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | AURKA | O14965 | 2/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11420987 | 0.73 | PPOX (0.46) | CES1PPOXGSK3B | |
| SCHEMBL6796386 | 0.70 | PPOX (0.45) | CES1PPOXCHEK1CDK1CDK2 | |
| SCHEMBL13578767 | 0.68 | PPOX (0.48) | CES1TGM2PPOXCHEK1GSK3B | |
| SCHEMBL734206 | 0.68 | CES1 (1.00) | CES1TGM2DNMT1 | |
| SCHEMBL1413190 | 0.68 | PPOX (0.58) | CES1PPOXGSK3BDNMT1 | |
| SCHEMBL13578768 | 0.67 | PPOX (0.47) | CES1TGM2PPOXCHEK1GSK3B | |
| SCHEMBL3684157 | 0.67 | PPOX (0.47) | CES1PPOXCDK2GSK3BCDK4 | |
| SCHEMBL13578745 | 0.67 | PPOX (0.42) | CES1PPOXCHEK1GSK3BDNMT1 | |
| SCHEMBL13129894 | 0.65 | PPOX (0.41) | CES1PPOXCDK2KDRGSK3B | |
| SCHEMBL29279264 | 0.65 | CES1 (0.64) | CES1TGM2PPOXCHEK1CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4096145-A | DYES FOR RESINS AND POLYESTER TEXTILES | BASF AKTIENGESELLSCHAFT (DT) | 1978-06-20 | — | — | US | disclosed |