Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 17/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 15/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL675749 | 0.85 | HDAC6 (0.67) | HDAC6HDAC3NCOR2HDAC1HDAC8 | |
| SCHEMBL7311585 | 0.81 | HDAC6 (0.52) | HDAC6HDAC3NCOR2HDAC1HDAC8 | |
| SCHEMBL22608571 | 0.72 | HDAC6 (1.00) | HDAC6HDAC3NCOR2HDAC1HDAC8 | |
| SCHEMBL20236425 | 0.71 | HDAC1 (0.56) | HDAC6HDAC3NCOR2HDAC1HDAC8 | |
| SCHEMBL9943838 | 0.69 | HDAC6 (0.71) | HDAC6HDAC3NCOR2HDAC1HDAC8 | |
| SCHEMBL28431899 | 0.69 | HDAC6 (0.58) | HDAC6HDAC3NCOR2HDAC1HDAC8 | |
| SCHEMBL27642637 | 0.68 | GRIN2D (0.55) | HDAC6HDAC3NCOR2 | |
| SCHEMBL7322365 | 0.68 | HDAC6 (0.54) | HDAC6HDAC3NCOR2HDAC1HDAC8 | |
| SCHEMBL7322358 | 0.67 | HDAC6 (0.46) | HDAC6HDAC3NCOR2HDAC1HDAC8 | |
| Hydrochloric Acid SCHEMBL27432653 | 0.67 | HDAC6 (0.69) | HDAC6HDAC3NCOR2HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011018241-A1 | METHODS FOR THE IDENTIFICATION AND CHARACTERIZATION OF HDAC INTERACTING COMPOUNDS | CELLZOME AG (DE) | 2011-02-17 | — | — | WO | disclosed |