Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314094 | 0.89 | HDAC6 (0.48) | HDAC6HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL5175761 | 0.88 | HDAC6 (0.69) | HDAC6HDAC1HDAC8HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL7320637 | 0.87 | HDAC6 (0.68) | HDAC6HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL7320956 | 0.87 | HDAC6 (0.64) | HDAC6HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL7320904 | 0.86 | HDAC1 (0.58) | HDAC6HDAC1HDAC8HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL7321060 | 0.85 | HDAC1 (0.57) | HDAC6HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL7321083 | 0.84 | HDAC1 (0.63) | HDAC6HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL7322814 | 0.84 | HDAC6 (0.56) | HDAC6HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL7322140 | 0.84 | HDAC6 (0.47) | HDAC6HDAC1HDAC8HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL7312341 | 0.83 | HDAC6 (0.55) | HDAC6HDAC1HDAC8HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140051716-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | CERENO SCIENTIFIC AB | 2014-02-20 | — | — | US | disclosed |
| EP-0901465-B1 | COMPOUNDS WITH ANTI-INFLAMMATORY AND IMMUNOSUPPRESSIVE ACTIVITIES | ITALFARMACO SPA (IT) | 2000-09-27 | — | — | EP | disclosed |
| US-6034096-A | Compounds with anti-inflammatory and immunosuppressive activities | ITALFARMACO S.P.A. (IT) | 2000-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140051716-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | HDAC3, HDAC1, HDAC2 | HDAC6 10/4885HDAC1 2/4885HDAC8 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.