SCHEMBL1163522

SCHEMBL1163522

O=C1CCCC(Cl)(Cl)C1(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11684353 0.83
SCHEMBL10885747 0.75
SCHEMBL11756060 0.72
SCHEMBL3368035 0.70
SCHEMBL29165179 0.70 CRBN (0.33)
SCHEMBL10585028 0.68
SCHEMBL11537926 0.68
SCHEMBL8690864 0.66 KMT2A (0.34)
SCHEMBL1903325 0.65 CRBN (0.33)
SCHEMBL7071198 0.65 CRBN (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250277257-A1 HYBRIDIZATION COMPOSITIONS AND METHODS DAKO DENMARK APS (DK) 2025-09-04 US disclosed
CN-119638555-A Chemical structure and preparation method of pyrogallol and dimer diphenyl ether tetraphenol thereof 深圳有为技术控股集团有限公司 2025-03-18 CN disclosed
US-12209276-B2 Hybridization compositions and methods AGILENT TECHNOLOGIES, INC. (US) 2025-01-28 US disclosed
US-20240200124-A1 COMPOSITIONS AND METHODS FOR PERFORMING HYBRIDIZATIONS WITH NO DENATURATION DAKO DENMARK APS (DK) 2024-06-20 US disclosed
US-20240124922-A1 HYBRIDIZATION COMPOSITIONS AND METHODS DAKO DENMARK APS (DK) 2024-04-18 US disclosed
CN-220214880-U Trihydroxybenzaldehyde's synthesizer 福建未来药业有限公司 2023-12-22 CN disclosed
US-11834703-B2 Hybridization compositions and methods AGILENT TECHNOLOGIES, INC. (US) 2023-12-05 US disclosed
US-11795499-B2 Compositions and methods for performing hybridizations with separate denaturation of the sample and probe AGILENT TECHNOLOGIES, INC. (US) 2023-10-24 US disclosed
US-20220162683-A1 COMPOSITIONS AND METHODS FOR PERFORMING HYBRIDIZATIONS WITH NO DENATURATION DAKO DENMARK APS (DK) 2022-05-26 US disclosed
CN-110035992-B Process for preparing 3-substituted 2-vinylphenyl sulfonates 拜耳作物科学股份公司 2022-04-05 CN disclosed
US-4594438-A Dehydrohalogenation heating of 2,2,6-tri-halo-6-(1-halisobutyl)cyclohexanone MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) 1986-06-10 US disclosed
EP-0090976-B1 2,2-DIHALO-6-HALO-6(1-HALOISOBUTYL)CYCLOHEXANONE MITSUBISHI KASEI CORPORATION (JP) 1985-12-11 EP disclosed
US-4499306-A HALOGENATION OF 2-ISOBUTYLIDENE CYCLOHEXANONE IN PRESENCE OF CATALST MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1985-02-12 US disclosed
EP-0090976-A2 2,2-Dihalo-6-halo-6(1-haloisobutyl)cyclohexanone MITSUBISHI KASEI CORPORATION (JP) 1983-10-12 EP disclosed
US-4268694-A HYDROLYSIS OF TETRAHALOCYCLOHEXANONE FISONS LIMITED (GB) 1981-05-19 US disclosed
US-4267378-A 2,2-Dialkoxy-6-chlorocyclohexanones Van Winckel, Carl E. (CA) 1981-05-12 US disclosed
US-4250341-A 2,2,6,6-Tetrachloro (or bromo) cyclohexane and pyrogallol FISONS LIMITED (GB) 1981-02-10 US disclosed
US-4219505-A HALOGENATION OF A CYCLOHEXANOME WITH AN ORGANOPHOSPHOROUS CATALYST FISONS LIMITED (GB) 1980-08-26 US disclosed
US-4166914-A Production of o-alkoxyphenols Van Winckel, Carl E. (CA) 1979-09-04 US disclosed
US-3927106-A Preparation of tetrachlorocyclo-hexanone QO CHEMICALS, INC. 1975-12-16 US disclosed