Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28089037 | 1.00 | NAAA (0.52) | NAAASMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL16107540 | 0.87 | NAAA (0.55) | NAAASMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL1668081 | 0.87 | NAAA (0.55) | NAAASMN1; SMN2ALDH1A1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL4199638 | 0.87 | SMN1; SMN2 (0.48) | NAAASMN1; SMN2LMNAEPHX1MAPT | |
| SCHEMBL28163709 | 0.86 | HDAC3 (0.43) | SMN1; SMN2EPHX1HTT | |
| SCHEMBL28163708 | 0.86 | HDAC3 (0.43) | SMN1; SMN2EPHX1HTT | |
| SCHEMBL9780637 | 0.86 | NAAA (0.57) | NAAASMN1; SMN2ALDH1A1EPHX1HTT | |
| SCHEMBL11531764 | 0.86 | NAAA (0.57) | NAAASMN1; SMN2ALDH1A1EPHX1HTT | |
| SCHEMBL11348782 | 0.86 | NAAA (0.57) | NAAASMN1; SMN2ALDH1A1EPHX1HTT | |
| SCHEMBL3404981 | 0.86 | NAAA (0.57) | NAAASMN1; SMN2ALDH1A1EPHX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106349156-A | Pyridine-2-amides capable of being used as CB2 agonist | 霍夫曼-拉罗奇有限公司 | 2017-01-25 | — | — | CN | claimed |
| CN-103608332-B | Pyridine-2-amides useful as CB2 agonists | 霍夫曼-拉罗奇有限公司 | 2016-09-28 | — | — | CN | claimed |
| US-4117126-A | 7-(α-(4-Hydroxy-1,5-naphthyridine-3-carbonamido)-α-phenylacetamido) cephalosporin derivatives | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1978-09-26 | — | — | US | disclosed |
| US-4068074-A | BACTERICIDES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1978-01-10 | — | — | US | disclosed |
| US-4068074-A | BACTERICIDES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1978-01-10 | — | — | US | disclosed |
| US-4061748-A | BACTERICIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-12-06 | — | — | US | disclosed |