Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 11/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11636817 | 0.87 | KDM4E (0.55) | KMT2AMEN1ALDH1A1MAOBKDM4E | |
| SCHEMBL9390486 | 0.76 | MAOB (0.49) | KMT2AMEN1HSD17B10ALDH1A1MAOB | |
| SCHEMBL29180246 | 0.76 | MAOB (0.49) | KMT2AMEN1HSD17B10ALDH1A1MAOB | |
| SCHEMBL30558218 | 0.76 | MAOB (0.50) | MAOBMAOAPTPN1 | |
| SCHEMBL6203939 | 0.75 | MAOB (0.63) | MAOBMAOAPTPN1ADORA2B | |
| SCHEMBL11636931 | 0.75 | MAOB (0.47) | KMT2AMEN1HSD17B10ALDH1A1MAOB | |
| SCHEMBL11668249 | 0.74 | MAOB (0.57) | KMT2AMEN1ALDH1A1MAOBHTT | |
| SCHEMBL30558227 | 0.73 | MAOB (0.48) | MAOBMAOAPTPN1 | |
| SCHEMBL30963746 | 0.73 | MAOB (0.56) | KMT2AMEN1HSD17B10ALDH1A1MAOB | |
| SCHEMBL17943730 | 0.73 | MAOB (0.56) | KMT2AMEN1HSD17B10ALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4127669-A | [(4-Oxo-4H-1-benzopyran-3-yl)oxy] acetic acids and derivatives | WARNER-LAMBERT COMPANY (US) | 1978-11-28 | — | — | US | claimed |
| US-4127669-A | [(4-Oxo-4H-1-benzopyran-3-yl)oxy] acetic acids and derivatives | WARNER-LAMBERT COMPANY (US) | 1978-11-28 | — | — | US | disclosed |