Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 15/20 | 0.57 |
| ▸ | MAOA | P21397 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5761877 | 0.88 | TSHR (0.50) | MAOBMAOAMAPTPOLBKDM4E | |
| Ammonia Solution, Strong SCHEMBL5763481 | 0.87 | TSHR (0.49) | MAOBMAOAMAPTPOLBKDM4E | |
| SCHEMBL6203939 | 0.85 | MAOB (0.63) | MAOBMAOAADORA2BPTPN1 | |
| SCHEMBL17943730 | 0.80 | MAOB (0.56) | MAOBMAOAKDM4ELMNAALDH1A1 | |
| SCHEMBL30963746 | 0.80 | MAOB (0.56) | MAOBMAOAKDM4ELMNAALDH1A1 | |
| SCHEMBL4519275 | 0.78 | MAOB (0.72) | MAOBMAOAADORA2B | |
| SCHEMBL27516742 | 0.76 | MAOB (0.58) | MAOBMAOAMAPTPOLBL3MBTL1 | |
| SCHEMBL22445080 | 0.75 | MAOA (0.68) | MAOAMAPTKDM4EHTTSMN1; SMN2 | |
| SCHEMBL11636817 | 0.75 | KDM4E (0.55) | MAOBMAOAPOLBKDM4ESMN1; SMN2 | |
| SCHEMBL13134182 | 0.74 | MAOB (0.45) | MAOBMAOAMAPTPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4127669-A | [(4-Oxo-4H-1-benzopyran-3-yl)oxy] acetic acids and derivatives | WARNER-LAMBERT COMPANY (US) | 1978-11-28 | — | — | US | disclosed |