Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.46 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19718856 | 0.82 | ALDH1A1 (0.56) | ALDH1A1MAPTHSD17B10EPHX1NPC1 | |
| SCHEMBL1082701 | 0.82 | ALDH1A1 (0.56) | ALDH1A1MAPTHSD17B10EPHX1NPC1 | |
| SCHEMBL26081355 | 0.80 | ALDH1A1 (0.55) | ALDH1A1MAPTHSD17B10EPHX1NPC1 | |
| SCHEMBL4474350 | 0.78 | HSD17B10 (0.54) | ALDH1A1MAPTHSD17B10EPHX1NPC1 | |
| SCHEMBL2526511 | 0.78 | ALDH1A1 (0.53) | ALDH1A1MAPTHSD17B10EPHX1NPC1 | |
| SCHEMBL14696638 | 0.77 | ALDH1A1 (0.51) | ALDH1A1MAPTHSD17B10EPHX1NPC1 | |
| Ammonia Solution, Strong SCHEMBL11636588 | 0.74 | HSD17B10 (0.50) | ALDH1A1MAPTHSD17B10CA2 | |
| SCHEMBL28575842 | 0.73 | ALDH1A1 (0.47) | ALDH1A1MAPTHSD17B10EPHX1 | |
| SCHEMBL28978607 | 0.72 | ALDH1A1 (0.40) | ALDH1A1MAPTHSD17B10EPHX1NPC1 | |
| SCHEMBL14801937 | 0.70 | ALDH1A1 (0.44) | ALDH1A1MAPTHSD17B10EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4100170-A | ANTIHYPERTENSIVE AGENTS, MONOAMINE OXIDASE INHIBITORS | PENNWALT CORPORATION (US) | 1978-07-11 | — | — | US | disclosed |