Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11637702 | 0.89 | MAOA (0.66) | MAOAADRA1AMAPTAKR1C3AKR1C2 | |
| SCHEMBL11637743 | 0.87 | MAPT (0.42) | MAOAADRA1AMAPTPOLBGAA | |
| SCHEMBL11638633 | 0.85 | MAOA (0.54) | MAOAADRA1AMAPTPOLBGAA | |
| SCHEMBL11638582 | 0.84 | MAOA (0.51) | MAOAADRA1AMAPTAKR1C3AKR1C2 | |
| SCHEMBL11637527 | 0.84 | MAOA (0.51) | MAOAADRA1AMAPTAKR1C3AKR1C2 | |
| SCHEMBL11642466 | 0.83 | MAOA (0.56) | MAOAADRA1AMAPTAKR1C3AKR1C2 | |
| SCHEMBL11667804 | 0.82 | MAOA (0.55) | MAOAADRA1AMAPTAKR1C3AKR1C2 | |
| SCHEMBL11638535 | 0.81 | MAPT (0.44) | MAPTPOLBGAAKMT2AMEN1 | |
| SCHEMBL11638033 | 0.80 | MAOA (0.54) | MAOAADRA1AMAPTAKR1C3AKR1C2 | |
| SCHEMBL6782970 | 0.77 | MAOA (0.56) | MAOAADRA1AMAPTAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4100168-A | ANALGESICS, ANTIPYRETIC, ANTIINFLAMMATORY AGENTS | LILLY INDUSTRIES LTD. (GB) | 1978-07-11 | — | — | US | disclosed |