Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | RET | P07949 | 2/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30699386 | 0.90 | KDM4E (0.62) | ALDH1A1ADORA3KDM4EGAAKMT2A | |
| SCHEMBL11635383 | 0.87 | ALDH1A1 (0.66) | ALDH1A1RETADORA3KDM4EGAA | |
| SCHEMBL11636194 | 0.83 | ALDH1A1 (0.49) | ALDH1A1RETADORA3KDM4EGAA | |
| SCHEMBL11636031 | 0.81 | KDM4E (0.48) | ALDH1A1RETADORA3KDM4EGAA | |
| SCHEMBL28429303 | 0.80 | RET (0.63) | ALDH1A1RETADORA3KDM4EGAA | |
| SCHEMBL30807179 | 0.77 | CYP3A4 (0.77) | ALDH1A1RETADORA3KDM4EKMT2A | |
| SCHEMBL11636258 | 0.77 | ALDH1A1 (0.66) | ALDH1A1ADORA3KDM4EGAAKMT2A | |
| SCHEMBL19846946 | 0.76 | KMT2A (0.64) | ALDH1A1RETADORA3KDM4EGAA | |
| SCHEMBL28201174 | 0.75 | KDM4E (0.52) | ALDH1A1RETADORA3KDM4EGAA | |
| SCHEMBL11634332 | 0.75 | KDM4E (0.64) | ALDH1A1ADORA3KDM4EGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4097582-A | 6',2-(2'-Arylchromonyl) propionic acids, and analgesic and anti-inflammatory derivatives thereof | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1978-06-27 | — | — | US | disclosed |