Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | AR | P10275 | 3/20 | 0.50 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2399205 | 0.91 | SLC22A12 (0.50) | CYP19A1KDM4EARSLC22A12MAOB | |
| SCHEMBL7604105 | 0.86 | CYP19A1 (0.49) | CYP19A1KDM4EARSLC22A12MAOB | |
| SCHEMBL1242979 | 0.84 | KDM4E (0.65) | CYP19A1KDM4EARMAOBHSD17B10 | |
| SCHEMBL10361402 | 0.77 | MAOB (0.54) | CYP19A1KDM4EARSLC22A12MAOB | |
| SCHEMBL11050274 | 0.77 | PTPN1 (0.51) | CYP19A1ARMAOBMAPTPTPN1 | |
| SCHEMBL130267 | 0.76 | CYP19A1 (0.59) | CYP19A1KDM4EARSLC22A12MAOB | |
| SCHEMBL9205670 | 0.76 | CYP19A1 (0.59) | CYP19A1KDM4EARSLC22A12MAOB | |
| SCHEMBL4163503 | 0.74 | CYP19A1 (0.60) | CYP19A1KDM4EARMAOBHSD17B10 | |
| SCHEMBL6703206 | 0.74 | MAOB (0.59) | CYP19A1KDM4EARSLC22A12MAOB | |
| SCHEMBL10360963 | 0.74 | MAOB (0.59) | CYP19A1KDM4EARSLC22A12MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4105675-A | REDUCING ACYLATED FLAVANONE WITH ALKALI BOROHYDRIDE TO REMOVE OXYGEN FUNCTION AT 4-POSITION; OXIDIZING WITH HALOGENATED BENZOQUINONE TO FORM SALT | THE COCA-COLA COMPANY (US) | 1978-08-08 | — | — | US | disclosed |