Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CETP | P11597 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | UBE2N | P61088 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16078684 | 0.97 | LMNA (0.59) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL9904984 | 0.97 | LMNA (0.59) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL6945805 | 0.97 | LMNA (0.59) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL11636649 | 0.97 | LMNA (0.59) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL16078659 | 0.97 | LMNA (0.59) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL18929313 | 0.97 | LMNA (0.59) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL13456966 | 0.97 | LMNA (0.59) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL11633785 | 0.97 | LMNA (0.59) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL15389691 | 0.97 | LMNA (0.59) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL9524076 | 0.92 | LMNA (0.46) | LMNACYP2D6SPHK1GMNNPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022097287-A1 | THERAPEUTIC AGENT FOR PROGRESSIVE DISEASE CAUSED BY INCREASE IN EOMES-POSITIVE CD4-POSITIVE T CELLS | 国立研究開発法人国立精神・神経医療研究センター | 2022-05-12 | — | — | WO | disclosed |
| CN-105008380-B | Conjugate compound | 维多利亚联结有限公司 | 2018-01-23 | — | — | CN | disclosed |
| CN-105008380-A | Conjugated compounds | CALLAGHAN INNOVATION RES LTD | 2015-10-28 | — | — | CN | disclosed |
| US-4101589-A | SURFACTANTS, LUBRICANTS, URETHANES, ALKYD RESINS | PILOT CHEMICAL COMPANY (US) | 1978-07-18 | — | — | US | disclosed |