Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | STAT6 | P42226 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16700713 | 0.90 | FFAR3 (0.60) | FFAR3NFKB1MAPK1CYP2C19TP53 | |
| SCHEMBL11640019 | 0.80 | FFAR3 (0.36) | FFAR3SMN1; SMN2 | |
| SCHEMBL17893172 | 0.79 | FFAR3 (0.60) | FFAR3NFKB1MAPK1CYP2C19TP53 | |
| SCHEMBL264769 | 0.78 | — | — | |
| SCHEMBL25831449 | 0.78 | FFAR3 (0.35) | FFAR3 | |
| SCHEMBL405480 | 0.78 | FFAR3 (0.65) | FFAR3NFKB1MAPK1CYP2C19TP53 | |
| SCHEMBL4442780 | 0.78 | FFAR3 (0.65) | FFAR3NFKB1MAPK1CYP2C19TP53 | |
| SCHEMBL13490845 | 0.78 | FFAR3 (0.65) | FFAR3NFKB1MAPK1CYP2C19TP53 | |
| SCHEMBL14012097 | 0.78 | FFAR3 (0.65) | FFAR3NFKB1MAPK1CYP2C19TP53 | |
| SCHEMBL503244 | 0.78 | FFAR3 (0.65) | FFAR3NFKB1MAPK1CYP2C19TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313208-B | Bicyclic carboxamides and methods of use thereof | 泰普斯特医疗公司 | 2024-04-19 | — | — | CN | disclosed |
| US-4098823-A | VASODILATION, HYPOTENSIVE AGENTS, ANTICOAGULATNS, ANTISECRETORY AGENTS, INOTROPIC AGENTS | MILES LABORATORIES, INC. (US) | 1978-07-04 | — | — | US | disclosed |