Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 11/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11644936 | 0.89 | FFAR4 (0.45) | SLC6A2SLC6A3SLC6A4FFAR4HRH1 | |
| SCHEMBL11645611 | 0.87 | FFAR4 (0.44) | GABRR1SLC6A2SLC6A3SLC6A4FFAR4 | |
| SCHEMBL795203 | 0.80 | SLC6A4 (0.52) | SLC6A2SLC6A3SLC6A4FFAR4GRIN1 | |
| SCHEMBL26857799 | 0.76 | AKR1C3 (0.51) | SLC6A2SLC6A3SLC6A4FFAR4HRH1 | |
| SCHEMBL20046785 | 0.74 | SLC6A2 (0.57) | SLC6A2SLC6A3SLC6A4HRH1KCNH2 | |
| SCHEMBL30182887 | 0.74 | SLC6A2 (0.57) | SLC6A2SLC6A3SLC6A4HRH1KCNH2 | |
| SCHEMBL10188580 | 0.73 | FFAR4 (0.52) | SLC6A2SLC6A3SLC6A4FFAR4 | |
| SCHEMBL27878721 | 0.73 | FFAR4 (0.44) | SLC6A2SLC6A3SLC6A4FFAR4 | |
| SCHEMBL1749499 | 0.72 | ACSL1 (0.56) | SLC6A2SLC6A3SLC6A4HRH1 | |
| SCHEMBL5844291 | 0.69 | GABRR1 (0.94) | GABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088780-A | ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |
| US-4032655-A | PHENYLGUANIDINES USEFUL AS ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-06-28 | — | — | US | disclosed |
| US-4024176-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |
| US-4021571-A | ANTHELMINTICS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-03 | — | — | US | disclosed |
| US-4005123-A | ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-25 | — | — | US | disclosed |
| US-3993682-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |