Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 13/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11644936 | 0.89 | FFAR4 (0.45) | FFAR4SLC6A4SLC6A2SLC6A3HRH1 | |
| SCHEMBL11637990 | 0.87 | GABRR1 (0.45) | FFAR4SLC6A4SLC6A2SLC6A3GABRR1 | |
| SCHEMBL26857799 | 0.83 | AKR1C3 (0.51) | FFAR4SLC6A4SLC6A2SLC6A3HRH1 | |
| SCHEMBL10188580 | 0.78 | FFAR4 (0.52) | FFAR4SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL1749499 | 0.76 | ACSL1 (0.56) | SLC6A4SLC6A2SLC6A3HRH1EPHX2 | |
| SCHEMBL15574815 | 0.74 | SLC6A2 (0.52) | FFAR4SLC6A4SLC6A2SLC6A3HRH1 | |
| SCHEMBL15574817 | 0.74 | SLC6A2 (0.52) | FFAR4SLC6A4SLC6A2SLC6A3HRH1 | |
| SCHEMBL15574816 | 0.74 | SLC6A2 (0.52) | FFAR4SLC6A4SLC6A2SLC6A3HRH1 | |
| SCHEMBL795203 | 0.74 | SLC6A4 (0.52) | FFAR4SLC6A4SLC6A2SLC6A3HRH1 | |
| SCHEMBL3457973 | 0.73 | EPHX2 (0.44) | FFAR4EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088780-A | ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |
| US-4032655-A | PHENYLGUANIDINES USEFUL AS ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-06-28 | — | — | US | disclosed |
| US-4024176-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |
| US-4021571-A | ANTHELMINTICS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-03 | — | — | US | disclosed |
| US-4005123-A | ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-25 | — | — | US | disclosed |
| US-3993682-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |