Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17045730 | 0.84 | PARP1 (0.53) | MAPTKDM4EMAPK1NSD2KMT2A | |
| SCHEMBL11637894 | 0.80 | MAPT (0.46) | MAPTKDM4EMAPK1KMT2AMEN1 | |
| SCHEMBL11633105 | 0.79 | ADORA2A (0.41) | MAPTKDM4EMAPK1NSD2KMT2A | |
| SCHEMBL17045726 | 0.75 | PARP1 (0.42) | MAPTKDM4EMAPK1NSD2KMT2A | |
| SCHEMBL11060440 | 0.73 | BCL2 (0.50) | MAPTKDM4EMAPK1NSD2KMT2A | |
| SCHEMBL24317500 | 0.71 | CDK2 (0.44) | MAPTKDM4EKMT2APARP1MEN1 | |
| SCHEMBL7936537 | 0.71 | RAD52 (0.44) | MAPTKDM4EKMT2AMAOAADORA2A | |
| SCHEMBL11318564 | 0.71 | KMT2A (0.45) | MAPTKMT2APARP1MEN1GAA | |
| SCHEMBL11809624 | 0.71 | BCL2 (0.50) | MAPTKDM4EMAPK1NSD2KMT2A | |
| SCHEMBL52296 | 0.70 | KDM4E (0.62) | MAPTKDM4EMAPK1NSD2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4096145-A | DYES FOR RESINS AND POLYESTER TEXTILES | BASF AKTIENGESELLSCHAFT (DT) | 1978-06-20 | — | — | US | disclosed |