Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL1163885

CC(C)NC(=O)C(N)Cc1ccccc1.O=C(O)C(F)(F)F

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CTSC P53634 2/20 0.56
OPRK1 P41145 4/20 0.55
ALPI P09923 1/20 0.51
PKM P14618 1/20 0.51
PTGS1 P23219 1/20 0.51
XIAP P98170 1/20 0.51
SLC7A5 Q01650 1/20 0.51
CTRB1 P17538 3/20 0.51
LTA4H P09960 2/20 0.50
SLC15A1 P46059 1/20 0.49
CYP3A4 P08684 1/20 0.48
MAPK1 P28482 1/20 0.48
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL11026931 1.00 CTSC (0.56) CTSCOPRK1ALPIPKMPTGS1
SCHEMBL15421957 0.92 CTSC (0.63) CTSCOPRK1ALPIPKMPTGS1
SCHEMBL10800384 0.92 CTSC (0.63) CTSCOPRK1ALPIPKMPTGS1
SCHEMBL17877159 0.92 CTSC (0.63) CTSCOPRK1ALPIPKMPTGS1
Bromide SCHEMBL10803036 0.91 CTSC (0.61) CTSCOPRK1ALPIPKMPTGS1
Hydrochloric Acid SCHEMBL7765674 0.91 CTSC (0.61) CTSCOPRK1ALPIPKMPTGS1
Trifluoroacetic Acid SCHEMBL16050210 0.89 LTA4H (0.57) CTSCALPIPKMPTGS1XIAP
Trifluoroacetic Acid SCHEMBL8898599 0.87 CTSC (0.52) CTSCOPRK1ALPIPKMPTGS1
Trifluoroacetic Acid SCHEMBL4389285 0.86 CTSC (0.51) CTSCOPRK1ALPIPKMPTGS1
Trifluoroacetic Acid SCHEMBL6967778 0.85 SLC7A5 (0.54) CTSCOPRK1ALPIPKMPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2464974-A1 FUNCTIONALISATION OF SOLID SUBSTRATES UCL Business PLC (GB) 2012-06-20 EP disclosed
EP-2464972-A1 REVERSIBLE COVALENT LINKAGE OF FUNCTIONAL MOLECULES UCL Business PLC (GB) 2012-06-20 EP disclosed
WO-2011018613-A1 FUNCTIONALISATION OF SOLID SUBSTRATES UCL BUSINESS PLC (GB) 2011-02-17 WO disclosed
WO-2011018611-A1 REVERSIBLE COVALENT LINKAGE OF FUNCTIONAL MOLECULES UCL BUSINESS PLC (GB) 2011-02-17 WO disclosed