Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.53 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.52 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11641987 | 0.99 | SMN1; SMN2 (0.70) | SMN1; SMN2HTTCHRM2POLBLMNA | |
| SCHEMBL11642501 | 0.92 | SMN1; SMN2 (0.68) | SMN1; SMN2HTTCHRM2POLBLMNA | |
| SCHEMBL11640467 | 0.91 | HTT (0.69) | SMN1; SMN2HTTCHRM2POLBLMNA | |
| SCHEMBL14491525 | 0.81 | SMN1; SMN2 (0.68) | SMN1; SMN2HTTCHRM2LMNANPSR1 | |
| SCHEMBL9828039 | 0.81 | SMN1; SMN2 (0.68) | SMN1; SMN2HTTCHRM2LMNANPSR1 | |
| SCHEMBL9829676 | 0.81 | HTT (0.71) | SMN1; SMN2HTTCHRM2LMNANPSR1 | |
| SCHEMBL13067102 | 0.80 | SMN1; SMN2 (0.66) | SMN1; SMN2HTTCHRM2LMNANPSR1 | |
| SCHEMBL14067363 | 0.79 | SMN1; SMN2 (0.68) | SMN1; SMN2HTTCHRM2LMNANPSR1 | |
| SCHEMBL19242797 | 0.78 | HTT (0.68) | SMN1; SMN2HTTCHRM2LMNANPSR1 | |
| SCHEMBL19242796 | 0.78 | HTT (0.68) | SMN1; SMN2HTTCHRM2LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117144-A | ANTIDEPRESSANTS | AB KABI (SE) | 1978-09-26 | — | — | US | disclosed |
| US-3947451-A | TREATMENT OF PSYCHIATRIC AND PSYCHOSOMATIC DISEASES | AB KABI (SW) | 1976-03-30 | — | — | US | disclosed |