Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.57 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.55 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.54 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829676 | 0.94 | HTT (0.71) | SMN1; SMN2HTTLMNANPSR1L3MBTL1 | |
| SCHEMBL9829282 | 0.93 | SMN1; SMN2 (0.60) | SMN1; SMN2HTTLMNANPSR1L3MBTL1 | |
| SCHEMBL9831308 | 0.88 | SMN1; SMN2 (0.61) | SMN1; SMN2HTTLMNANPSR1L3MBTL1 | |
| SCHEMBL9831932 | 0.88 | HTT (0.75) | SMN1; SMN2HTTLMNANPSR1L3MBTL1 | |
| SCHEMBL13067102 | 0.85 | SMN1; SMN2 (0.66) | SMN1; SMN2HTTLMNANPSR1L3MBTL1 | |
| SCHEMBL14491525 | 0.83 | SMN1; SMN2 (0.68) | SMN1; SMN2HTTLMNANPSR1L3MBTL1 | |
| SCHEMBL19242797 | 0.83 | HTT (0.68) | SMN1; SMN2HTTLMNANPSR1L3MBTL1 | |
| SCHEMBL19242796 | 0.83 | HTT (0.68) | SMN1; SMN2HTTLMNANPSR1L3MBTL1 | |
| SCHEMBL11640416 | 0.81 | SMN1; SMN2 (0.68) | SMN1; SMN2HTTLMNANPSR1L3MBTL1 | |
| SCHEMBL9829124 | 0.81 | SMN1; SMN2 (0.68) | SMN1; SMN2HTTLMNANPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |