Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 1/20 | 0.49 |
| ▸ | IL6 | P05231 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11636238 | 0.90 | HPSE (0.55) | CSNK1DIL6STAT3HPSEKCNH2 | |
| SCHEMBL2437918 | 0.89 | NPC1 (0.56) | CSNK1DIL6STAT3HPSEGAA | |
| SCHEMBL6614738 | 0.88 | HDAC6 (0.53) | CSNK1DIL6STAT3HPSEMAPT | |
| SCHEMBL11637058 | 0.85 | PSEN1 (0.46) | CSNK1DIL6STAT3HPSEMAPT | |
| SCHEMBL2436176 | 0.81 | NPC1 (0.59) | CSNK1DHPSERAF1BRAFNPC1 | |
| SCHEMBL7659834 | 0.80 | KDM4E (0.52) | IL6STAT3HPSEMAPTGAA | |
| SCHEMBL7429665 | 0.80 | NPC1 (0.53) | IL6STAT3HPSEMAPTGAA | |
| SCHEMBL2429205 | 0.80 | NPC1 (0.66) | CSNK1DIL6STAT3MAPTGAA | |
| SCHEMBL14371695 | 0.79 | GAA (0.50) | CSNK1DHPSEMAPTGAAMEN1 | |
| SCHEMBL11640133 | 0.79 | CSNK1D (0.48) | CSNK1DIL6STAT3GAAPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4100168-A | ANALGESICS, ANTIPYRETIC, ANTIINFLAMMATORY AGENTS | LILLY INDUSTRIES LTD. (GB) | 1978-07-11 | — | — | US | disclosed |