Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.74 |
| ▸ | LTA4H | P09960 | 2/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CARM1 | Q86X55 | 4/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | FNTA | P49354 | 1/20 | 0.49 |
| ▸ | FNTB | P49356 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11642831 | 0.86 | XIAP (0.56) | XIAPLTA4HTAAR1ALDH1A1LMNA | |
| SCHEMBL11646196 | 0.85 | XIAP (1.00) | XIAPLTA4HTAAR1ALDH1A1LMNA | |
| SCHEMBL11642853 | 0.84 | XIAP (0.70) | XIAPLTA4HTAAR1ALDH1A1HTT | |
| SCHEMBL15623783 | 0.83 | XIAP (0.68) | XIAPLTA4HTAAR1ALDH1A1HTT | |
| SCHEMBL1978265 | 0.83 | XIAP (0.58) | XIAPLTA4HTAAR1LMNAGAA | |
| SCHEMBL11642962 | 0.82 | XIAP (0.64) | XIAPLTA4HTAAR1ALDH1A1GAA | |
| SCHEMBL11645678 | 0.81 | XIAP (0.62) | XIAPLTA4HTAAR1ALDH1A1LMNA | |
| SCHEMBL16888002 | 0.81 | XIAP (0.62) | XIAPLTA4HTAAR1ALDH1A1LMNA | |
| SCHEMBL13821439 | 0.81 | ESRRA (0.59) | LTA4HALDH1A1LMNAGAAHTT | |
| SCHEMBL1978552 | 0.80 | XIAP (0.55) | XIAPLTA4HTAAR1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088780-A | ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |
| US-4032655-A | PHENYLGUANIDINES USEFUL AS ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-06-28 | — | — | US | disclosed |
| US-4024176-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |
| US-3993682-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |