Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 1.00 |
| ▸ | LTA4H | P09960 | 2/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.55 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.54 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ESRRA | P11474 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | PNLIP | P16233 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11645391 | 0.87 | XIAP (0.77) | XIAPLTA4HTAAR1CARM1PRMT6 | |
| SCHEMBL11640639 | 0.85 | XIAP (0.74) | XIAPLTA4HTAAR1CARM1PRMT6 | |
| SCHEMBL11642853 | 0.83 | XIAP (0.70) | XIAPLTA4HTAAR1SMN1; SMN2RAB9A | |
| SCHEMBL15623783 | 0.82 | XIAP (0.68) | XIAPLTA4HTAAR1CARM1PRMT6 | |
| SCHEMBL11643107 | 0.81 | XIAP (0.68) | XIAPLTA4HTAAR1CARM1PRMT6 | |
| SCHEMBL11643151 | 0.80 | XIAP (0.66) | XIAPLTA4HTAAR1CARM1PRMT6 | |
| SCHEMBL1701888 | 0.79 | XIAP (0.65) | XIAPMEN1KMT2AMAPTLMNA | |
| SCHEMBL11642962 | 0.78 | XIAP (0.64) | XIAPLTA4HTAAR1CARM1PRMT6 | |
| SCHEMBL11642254 | 0.78 | XIAP (0.64) | XIAPLTA4HMEN1KMT2AMAPT | |
| SCHEMBL11648371 | 0.77 | XIAP (0.63) | XIAPLTA4HTAAR1CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088780-A | ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |
| US-4032655-A | PHENYLGUANIDINES USEFUL AS ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-06-28 | — | — | US | disclosed |
| US-4024176-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |
| US-4021571-A | ANTHELMINTICS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-03 | — | — | US | disclosed |
| US-4005123-A | ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-25 | — | — | US | disclosed |
| US-3993682-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |