⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8119796 | 0.92 | — | — | |
| SCHEMBL22635006 | 0.90 | KDM4E (0.76) | — | |
| SCHEMBL1681641 | 0.83 | — | — | |
| SCHEMBL1900471 | 0.83 | KDM4E (0.82) | — | |
| SCHEMBL860791 | 0.83 | KDM4E (0.94) | — | |
| SCHEMBL14740196 | 0.80 | KDM4E (1.00) | — | |
| SCHEMBL14739904 | 0.80 | KDM4E (1.00) | — | |
| SCHEMBL1900654 | 0.80 | KDM4E (1.00) | — | |
| SCHEMBL14740132 | 0.80 | KDM4E (1.00) | — | |
| SCHEMBL14739632 | 0.80 | KDM4E (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010645-A | Preparation method of melatonin | 广西师范大学 | 2022-09-06 | — | — | CN | claimed |
| EP-4463457-B1 | PYRROLO[1,2-B]-2-PYRIDAZINONE COMPOUNDS AS 5-HT4 RECEPTOR AGONISTS | SUVEN LIFE SCIENCES LTD (IN) | 2026-02-04 | — | — | EP | disclosed |
| US-20250154191-A1 | OLIGONUCLEOTIDE PRODUCTION METHOD | LIID PHARMACEUTICALS, INC. (JP) | 2025-05-15 | — | — | US | disclosed |
| US-12275746-B2 | Pyrrolo[1,2-b]-2-pyridazinone compounds as 5-HT4 receptor agonists | SUVEN LIFE SCIENCES LIMITED (IN) | 2025-04-15 | — | — | US | disclosed |
| US-20250019386-A1 | PYRROLO[1,2-b]-2-PYRIDAZINONE COMPOUNDS AS 5-HT4 RECEPTOR AGONISTS | SUVEN LIFE SCIENCES LIMITED (IN) | 2025-01-16 | — | — | US | disclosed |
| EP-4450512-A1 | OLIGONUCLEOTIDE PRODUCTION METHOD | LIID Pharmaceuticals, Inc. (JP) | 2024-10-23 | — | — | EP | disclosed |
| US-11725000-B2 | Apoptosis inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2023-08-15 | — | — | US | disclosed |
| WO-2023113038-A1 | OLIGONUCLEOTIDE PRODUCTION METHOD | リードファーマ株式会社 | 2023-06-22 | — | — | WO | disclosed |
| CN-111727186-B | Biheterocyclic substituted pyridine-2 (1H) -ketone derivative, preparation method and medical application thereof | 上海海雁医药科技有限公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |
| US-20080255085-A1 | Novel Imidazo [4,5-b] Pyridine Derivatives as Inhibitors of Glycogen Synthase Kinase 3 for Use in the Treatment of Dementia and Neurodegenerative Disorders | ASTRAZENECA AB (SE) | 2008-10-16 | — | — | US | disclosed |
| US-20080255085-A1 | Novel Imidazo [4,5-b] Pyridine Derivatives as Inhibitors of Glycogen Synthase Kinase 3 for Use in the Treatment of Dementia and Neurodegenerative Disorders | ASTRAZENECA AB (SE) | 2008-10-16 | — | — | US | disclosed |
| EP-1947105-A1 | Method for single-step attachment of a label to target molecules | Mirus Bio Corporation (US) | 2008-07-23 | — | — | EP | disclosed |
| EP-1937680-A2 | NOVEL IMIDAZO [4,5 -B] PYRIDINE DERIVATIVES AS INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 FOR USE IN THE TREATMENT OF DEMENTIA AND NEURODEGENERATIVE DISORDERS | AstraZeneca AB (SE) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007040438-A2 | NOVEL IMIDAZO [4,5 -B] PYRIDINE DERIVATIVES AS INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 FOR USE IN THE TREATMENT OF DEMENTIA AND NEURODEGENERATIVE DISORDERS | ASTRAZENECA AB (SE) | 2007-04-12 | — | — | WO | disclosed |
| EP-1082110-B1 | USE OF COMPOUNDS FOR THE ELEVATION OF PYRUVATE DEHYDROGENASE ACTIVITY | ASTRAZENECA AB (SE) | 2004-03-24 | — | — | EP | disclosed |
| CN-1303281-A | Application of compound in enhancing activity of pyruvate dehydrogenase | ASTRA ZENECA LTD (SE) | 2001-07-11 | — | — | CN | disclosed |
| EP-0024510-B1 | PHENOXYPROPYL AMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1983-10-19 | — | — | EP | disclosed |
| US-4293557-A | AMIDES | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1981-10-06 | — | — | US | disclosed |
| EP-0024510-A1 | Phenoxypropyl amine derivatives, process for their preparation, and pharmaceutical compositions containing them | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1981-03-11 | — | — | EP | disclosed |