Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.82 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.82 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.82 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | F13A1 | P00488 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL860791 | 0.93 | KDM4E (0.94) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL21306389 | 0.91 | PAOX (0.74) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL14739632 | 0.90 | KDM4E (1.00) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL10937726 | 0.90 | KDM4E (1.00) | KDM4EMAPK1HIF1APAOXADRA1A | |
| Hexamethylenebisacetamide SCHEMBL61980 | 0.90 | KDM4E (1.00) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL14740132 | 0.90 | KDM4E (1.00) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL1847535 | 0.90 | KDM4E (1.00) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL14739904 | 0.90 | KDM4E (1.00) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL6516953 | 0.90 | KDM4E (1.00) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL1900654 | 0.90 | KDM4E (1.00) | KDM4EMAPK1HIF1APAOXADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0192299-B1 | PROCESS FOR THE PREPARATION OF PYRIMIDINE AND 2-ALKYLPYRIMIDINE | STAMICARBON B.V. (NL) | 1990-08-29 | — | — | EP | claimed |
| EP-0131374-B1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PENEM DERIVATIVES | PFIZER INC. (US) | 1988-11-23 | — | — | EP | claimed |
| US-4775755-A | DIAMINOPROPANE OR TETRAHYDROPYRIMIDINE REACTED WITH FORMAMIDE | STAMICARBON B. V. (NL) | 1988-10-04 | — | — | US | claimed |
| US-4619783-A | BACTERICIDES | PFIZER INC. (US) | 1986-10-28 | — | — | US | claimed |
| EP-0192299-A1 | Process for the preparation of pyrimidine and 2-alkylpyrimidine | STAMICARBON B.V. (NL) | 1986-08-27 | — | — | EP | claimed |
| US-20240239934-A1 | FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE | TOSOH CORPORATION (JP) | 2024-07-18 | — | — | US | disclosed |
| EP-3157978-B1 | STRICTLY SEGMENTED THERMOPLASTIC ELASTOMERS AS BIODEGRADABLE BIOMATERIALS | SYMO CHEM B V (NL) | 2021-08-11 | — | — | EP | disclosed |
| EP-3778573-A1 | COMPOUND WITH ANTICANCER ACTIVITY | Kyowa Kirin Co., Ltd. (JP) | 2021-02-17 | — | — | EP | disclosed |
| US-10562767-B2 | Liquid-organic hydrogen carrier systems based on catalytic peptide formation and hydrogenation | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2020-02-18 | — | — | US | disclosed |
| WO-2019189778-A1 | COMPOUND WITH ANTICANCER ACTIVITY | 協和発酵キリン株式会社 | 2019-10-03 | — | — | WO | disclosed |
| US-20170283257-A1 | LIQUID-ORGANIC HYDROGEN CARRIER SYSTEMS BASED ON CATALYTIC PEPTIDE FORMATION AND HYDROGENATION | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2017-10-05 | — | — | US | disclosed |
| EP-3189006-A1 | LIQUID-ORGANIC HYDROGEN CARRIER SYSTEMS BASED ON CATALYTIC PEPTIDE FORMATION AND HYDROGENATION | Yeda Research and Development Co., Ltd. (IL) | 2017-07-12 | — | — | EP | disclosed |
| US-6583164-B1 | Lyophilized imidazole-1-yl or 1,2,4-triazole-1-yl quaternized with a alklycarbonyloxy alkyl group eliminated in vivo; a saccharide; 4-acetoxymethyl-1-(3-(2-oxo-3-(4-(1H-tetrazol-yl) phenyl)-1-imidazolydinyl)butyl)-1H-1,2,4-triazolium chloride | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-06-24 | — | — | US | disclosed |
| US-5421868-A | Ink composition | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1995-06-06 | — | — | US | disclosed |
| US-5173112-A | Nonplugging, improved storage stability | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-12-22 | — | — | US | disclosed |
| EP-0192299-B1 | PROCESS FOR THE PREPARATION OF PYRIMIDINE AND 2-ALKYLPYRIMIDINE | STAMICARBON B.V. (NL) | 1990-08-29 | — | — | EP | disclosed |
| US-4775755-A | DIAMINOPROPANE OR TETRAHYDROPYRIMIDINE REACTED WITH FORMAMIDE | STAMICARBON B. V. (NL) | 1988-10-04 | — | — | US | disclosed |
| US-4775755-A | DIAMINOPROPANE OR TETRAHYDROPYRIMIDINE REACTED WITH FORMAMIDE | STAMICARBON B. V. (NL) | 1988-10-04 | — | — | US | disclosed |
| EP-0192299-A1 | Process for the preparation of pyrimidine and 2-alkylpyrimidine | STAMICARBON B.V. (NL) | 1986-08-27 | — | — | EP | disclosed |
| EP-0192299-A1 | Process for the preparation of pyrimidine and 2-alkylpyrimidine | STAMICARBON B.V. (NL) | 1986-08-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10562767-B2 | Liquid-organic hydrogen carrier systems based on catalytic peptide formation and hydrogenation | DDC, ADH1C, MLEC | KDM4E 2373/4885MAPK1 3077/4885HIF1A 2893/4885 |
| US-20170283257-A1 | LIQUID-ORGANIC HYDROGEN CARRIER SYSTEMS BASED ON CATALYTIC PEPTIDE FORMATION AND HYDROGENATION | DDC, ADH1C, MLEC | KDM4E 2373/4885MAPK1 3077/4885HIF1A 2893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.