Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11587048 | 0.81 | ALDH1A1 (0.40) | KMT2AALDH1A1SMN1; SMN2MEN1MAPK1 | |
| SCHEMBL10430901 | 0.81 | ALDH1A1 (0.40) | KMT2AALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL11642974 | 0.73 | KMT2A (0.33) | KMT2ALMNA | |
| SCHEMBL11641585 | 0.73 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL16710261 | 0.72 | KDM4E (0.45) | KMT2AALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL11643542 | 0.70 | GAA (0.48) | KMT2AALDH1A1SMN1; SMN2MEN1MAPK1 | |
| SCHEMBL11641013 | 0.68 | SMN1; SMN2 (0.42) | KMT2AALDH1A1SMN1; SMN2MEN1MAPK1 | |
| SCHEMBL22214077 | 0.67 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2GRM5 | |
| SCHEMBL3963159 | 0.65 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2GRM5 | |
| SCHEMBL16864083 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4130710-A | POLYOLEFIN STABILIZERS | CIBA-GEIGY CORPORATION (US) | 1978-12-19 | — | — | US | claimed |
| US-4130710-A | POLYOLEFIN STABILIZERS | CIBA-GEIGY CORPORATION (US) | 1978-12-19 | — | — | US | disclosed |