Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11641044 | 0.93 | CYP2A6 (0.50) | LMNACYP2A6CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11646616 | 0.88 | CYP19A1 (0.47) | LMNACYP2A6CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11646605 | 0.88 | CYP11B1 (0.47) | LMNACYP2A6CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11644185 | 0.87 | CYP2A6 (0.49) | LMNACYP2A6CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11641542 | 0.86 | TSHR (0.46) | LMNACYP2A6CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11644694 | 0.86 | IDO1 (0.48) | LMNACYP2A6CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11647848 | 0.83 | CYP19A1 (0.53) | LMNACYP2A6CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11641073 | 0.83 | CYP19A1 (0.47) | LMNACYP2A6CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11645655 | 0.82 | LMNA (0.52) | LMNACYP2A6CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11646627 | 0.81 | CYP2A6 (0.50) | LMNACYP2A6CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4123542-A | FUNGICIDES, BACTERICIDES, ANTIPROTOZOAL AGENTS | SYNTEX (U.S.A.) INC. (US) | 1978-10-31 | — | — | US | disclosed |