Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | XIAP | P98170 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1748983 | 0.90 | TAAR1 (0.64) | MEN1KMT2ATAAR1MAPTRAB9A | |
| SCHEMBL11643924 | 0.86 | MAPT (0.46) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11691127 | 0.86 | MEN1 (0.56) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11644745 | 0.86 | MEN1 (0.56) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11643649 | 0.86 | TAAR1 (0.69) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11644294 | 0.86 | MEN1 (0.56) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21306029 | 0.86 | MEN1 (0.56) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11645266 | 0.84 | MEN1 (0.55) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11644342 | 0.83 | MEN1 (0.54) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11648305 | 0.83 | LMNA (0.58) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088780-A | ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |
| US-4032655-A | PHENYLGUANIDINES USEFUL AS ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-06-28 | — | — | US | disclosed |
| US-4024176-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |
| US-3993682-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |