Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11689526 | 0.92 | XIAP (0.46) | XIAPMTNR1BMAPTALDH1A1POLB | |
| SCHEMBL11645332 | 0.89 | MTNR1B (0.53) | XIAPMTNR1BRAB9AMAPTHPGD | |
| SCHEMBL11645434 | 0.88 | XIAP (0.58) | XIAPMTNR1BRAB9AMAPTHPGD | |
| SCHEMBL11642384 | 0.87 | MTNR1B (0.61) | XIAPMTNR1BRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL11646067 | 0.87 | XIAP (0.54) | XIAPMTNR1BRAB9AMAPTHPGD | |
| SCHEMBL11642716 | 0.87 | MTNR1B (0.64) | XIAPMTNR1BRAB9AHPGDALDH1A1 | |
| SCHEMBL11646697 | 0.86 | MTNR1B (0.45) | MTNR1BRAB9AMAPTHPGDALDH1A1 | |
| SCHEMBL11641419 | 0.86 | XIAP (0.49) | XIAPMTNR1BRAB9AALDH1A1POLB | |
| SCHEMBL11643262 | 0.86 | XIAP (0.59) | XIAPMTNR1BRAB9AMAPTHPGD | |
| SCHEMBL11644482 | 0.86 | XIAP (0.60) | XIAPMTNR1BMAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088780-A | ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |
| US-4024176-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |
| US-3993682-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |