SCHEMBL11645299

SCHEMBL11645299

C=CCn1c(=O)oc(=O)c2cc(OC)c(OC)cc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
TNFRSF1A P19438 4/20 0.41
HCRTR1 O43613 1/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.37
HSD17B10 Q99714 2/20 0.37
HPGD P15428 1/20 0.37
KDM4E B2RXH2 4/20 0.37
CBX7 O95931 1/20 0.37
CDYL2 Q8N8U2 1/20 0.37
CDYL Q9Y232 1/20 0.37
CDY1; CDY1B Q9Y6F8 1/20 0.37
LMNA P02545 1/20 0.37
TSHR P16473 1/20 0.37
ALDH1A1 P00352 2/20 0.36
ELANE P08246 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28357440 0.78 TNFRSF1A (0.45) KMT2AMEN1TNFRSF1AHCRTR1ATM
SCHEMBL2859999 0.75 KDM4E (0.53) RXFP1SMN1; SMN2KDM4ELMNATSHR
SCHEMBL10803913 0.75 PTGER4 (0.49) KMT2AMEN1HSD17B10HPGDKDM4E
SCHEMBL30929112 0.74 PDE10A (0.43) KMT2AMEN1SMN1; SMN2HSD17B10HPGD
SCHEMBL1318339 0.74 PDE10A (0.43) KMT2AMEN1SMN1; SMN2HSD17B10HPGD
SCHEMBL3859196 0.73 CD74 (0.44) KMT2AMEN1ATMCBX7CDYL2
SCHEMBL4593193 0.73 HSP90AA1 (0.46) RXFP1KMT2AMEN1HCRTR1HSD17B10
SCHEMBL11260335 0.71 LMNA (0.38) KMT2AMEN1L3MBTL1SMN1; SMN2KDM4E
SCHEMBL11372364 0.70 RXFP1 (0.62) RXFP1KMT2AMEN1HSD17B10HPGD
SCHEMBL11485598 0.70 RXFP1 (0.52) RXFP1KMT2AMEN1TNFRSF1AHCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4117137-A DECYCLIZATION OF A 3-AZAISATOIC ANHYDRIDE SANDOZ, INC. (US) 1978-09-26 US disclosed