Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 7/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8342532 | 0.84 | — | — | |
| SCHEMBL11300738 | 0.77 | MAP3K14 (0.41) | MAP3K14CRBNCYP19A1 | |
| SCHEMBL31091776 | 0.77 | MAP3K14 (0.41) | MAP3K14CRBNCYP19A1LMNAALDH1A1 | |
| SCHEMBL4542045 | 0.75 | MAP3K14 (0.40) | MAP3K14CRBNCYP19A1 | |
| SCHEMBL5909391 | 0.69 | MAP3K14 (0.55) | MAP3K14CRBNCYP19A1KMT2AIDO1 | |
| SCHEMBL18475385 | 0.69 | CRBN (0.46) | MAP3K14CRBNTDP1ALDH1A1DDB1 | |
| Formic Acid SCHEMBL31232883 | 0.68 | MAP3K14 (0.34) | MAP3K14 | |
| SCHEMBL6897659 | 0.67 | — | — | |
| SCHEMBL23332645 | 0.65 | — | — | |
| SCHEMBL10053017 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4116875-A | Multifunctional substituted triazine functional fluid additives and compositions containing same | MOBIL OIL CORPORATION (US) | 1978-09-26 | — | — | US | disclosed |
| US-4113725-A | PYRIMIDINE-PYRROLIDONE COMPOUND, DETERGENTS, ANTIOXIDANTS | MOBIL OIL CORPORATION (US) | 1978-09-12 | — | — | US | disclosed |