Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | PFKFB2 | O60825 | 6/20 | 0.54 |
| ▸ | PFKFB3 | Q16875 | 6/20 | 0.54 |
| ▸ | PFKFB1 | P16118 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | IL18 | Q14116 | 1/20 | 0.54 |
| ▸ | AS3MT | Q9HBK9 | 3/20 | 0.52 |
| ▸ | NSD2 | O96028 | 2/20 | 0.52 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.52 |
| ▸ | FNTA | P49354 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11644978 | 0.91 | MCHR1 (0.56) | MAPK1POLBHTTALDH1A1MITF | |
| SCHEMBL11642720 | 0.87 | PFKFB2 (0.60) | MAPK1POLBPFKFB2PFKFB3PFKFB1 | |
| SCHEMBL11645090 | 0.86 | KMT2A (0.71) | MAPK1POLBALDH1A1PFKFB2PFKFB3 | |
| SCHEMBL11644514 | 0.86 | ALDH1A1 (0.73) | MAPK1POLBHTTALDH1A1MITF | |
| SCHEMBL11644159 | 0.84 | HPGD (0.67) | MAPK1POLBHTTALDH1A1MITF | |
| SCHEMBL11648050 | 0.84 | POLB (0.58) | MAPK1POLBHTTALDH1A1MITF | |
| SCHEMBL11640199 | 0.84 | TP53 (0.62) | MAPK1POLBHTTALDH1A1MITF | |
| SCHEMBL11637623 | 0.84 | POLB (0.62) | MAPK1POLBHTTALDH1A1MITF | |
| SCHEMBL31503982 | 0.82 | MEN1 (0.62) | MAPK1POLBALDH1A1MEN1MAPT | |
| SCHEMBL11640922 | 0.82 | ALDH1A1 (0.56) | MAPK1POLBHTTALDH1A1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088780-A | ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |
| US-4032655-A | PHENYLGUANIDINES USEFUL AS ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-06-28 | — | — | US | disclosed |
| US-4024176-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |
| US-3993682-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |