SCHEMBL11645926

SCHEMBL11645926

Cc1cc(C)c(O)c(C(C)(C)c2ccc(C(C)(C)c3cc(C)cc(C)c3O)cc2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
CA2 P00918 2/20 0.48
POLB P06746 1/20 0.48
TYR P14679 1/20 0.48
ESR1 P03372 6/20 0.45
HSD17B2 P37059 1/20 0.45
CYP2C9 P11712 3/20 0.44
CYP2C19 P33261 3/20 0.44
CYP1A2 P05177 1/20 0.44
KDM4E B2RXH2 1/20 0.42
LMNA P02545 1/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
ESR2 Q92731 5/20 0.41
HSD17B10 Q99714 2/20 0.41
CYP3A4 P08684 2/20 0.41
AR P10275 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29612050 0.87 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2CA2POLBTYR
SCHEMBL278790 0.87 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2CA2POLBTYR
SCHEMBL11648641 0.87 ESR1 (0.47) ALDH1A1SMN1; SMN2CA2POLBTYR
SCHEMBL3655091 0.83 ESR1 (0.52) ALDH1A1SMN1; SMN2CA2POLBTYR
SCHEMBL13609973 0.81 ESR1 (0.59) ALDH1A1TYRESR1CYP2C9CYP2C19
SCHEMBL38838 0.79 SMN1; SMN2 (0.77) ALDH1A1SMN1; SMN2CA2POLBTYR
SCHEMBL29364506 0.79 SMN1; SMN2 (0.77) ALDH1A1SMN1; SMN2CA2POLBTYR
SCHEMBL5318298 0.79 SMN1; SMN2 (0.77) ALDH1A1SMN1; SMN2CA2POLBTYR
SCHEMBL9576167 0.78 POLB (0.45) ALDH1A1SMN1; SMN2CA2POLBTYR
Butylated Hydroxytoluene SCHEMBL5514381 0.77 ALDH1A1 (0.82) ALDH1A1SMN1; SMN2CA2POLBTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4073746-A Mixtures of α,α'-bis-(2-hydroxy-3,5-dialkylphenyl)-p-and -m-diisopropylbenzenes, a process for the preparation thereof and the use thereof as stabilizers BAYER AKTIENGESELLSCHAFT (DT) 1978-02-14 US claimed
US-4116932-A MIXTURE OF ALPHA, ALPHA'-BIS(2-HYDROXY-3,5-DIALKYLPHENYL)DIISOPROPYLBENZENES BAYER AKTIENGESELLSCHAFT (DE) 1978-09-26 US disclosed
US-4073746-A Mixtures of α,α'-bis-(2-hydroxy-3,5-dialkylphenyl)-p-and -m-diisopropylbenzenes, a process for the preparation thereof and the use thereof as stabilizers BAYER AKTIENGESELLSCHAFT (DT) 1978-02-14 US disclosed