Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 3/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11652028 | 1.00 | LMNA (0.50) | LMNAGSTK1DNM1TSHRTHRB | |
| SCHEMBL11649299 | 1.00 | LMNA (0.50) | LMNAGSTK1DNM1TSHRTHRB | |
| SCHEMBL28990461 | 0.93 | LMNA (0.56) | LMNAGSTK1DNM1TSHRTHRB | |
| SCHEMBL1610425 | 0.93 | LMNA (0.56) | LMNAGSTK1DNM1TSHRTHRB | |
| SCHEMBL28990467 | 0.93 | LMNA (0.56) | LMNAGSTK1DNM1TSHRTHRB | |
| SCHEMBL23214473 | 0.93 | LMNA (0.56) | LMNAGSTK1DNM1TSHRTHRB | |
| SCHEMBL14353349 | 0.93 | LMNA (0.56) | LMNAGSTK1DNM1TSHRTHRB | |
| SCHEMBL9819038 | 0.93 | LMNA (0.56) | LMNAGSTK1DNM1TSHRTHRB | |
| SCHEMBL8883930 | 0.93 | LMNA (0.56) | LMNAGSTK1DNM1TSHRTHRB | |
| SCHEMBL4342318 | 0.93 | LMNA (0.56) | LMNAGSTK1DNM1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4087271-A | 1,2-Bis (thioalkyl) alkanes and derivatives thereof as abscission agents | THE PROCTER & GAMBLE COMPANY (US) | 1978-05-02 | — | — | US | disclosed |