Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17282769 | 0.79 | CA2 (0.40) | CA2ESR1KCNH2ALDH1A1POLB | |
| SCHEMBL1412323 | 0.79 | CA2 (0.40) | CA2ESR1KCNH2ALDH1A1POLB | |
| SCHEMBL1412322 | 0.79 | CA2 (0.40) | CA2ESR1KCNH2ALDH1A1POLB | |
| SCHEMBL13196035 | 0.79 | CA2 (0.40) | CA2ESR1KCNH2ALDH1A1POLB | |
| SCHEMBL1681789 | 0.79 | CA2 (0.40) | CA2ESR1KCNH2ALDH1A1POLB | |
| SCHEMBL11649386 | 0.78 | CA2 (0.36) | CA2ESR1KCNH2ALDH1A1POLB | |
| SCHEMBL865062 | 0.78 | CA2 (0.43) | CA2ESR1KCNH2ALDH1A1POLB | |
| SCHEMBL5126776 | 0.77 | CA2 (0.39) | CA2ESR1KCNH2ALDH1A1POLB | |
| SCHEMBL5532723 | 0.77 | CA2 (0.39) | CA2ESR1KCNH2ALDH1A1POLB | |
| SCHEMBL836707 | 0.77 | CA2 (0.39) | CA2ESR1KCNH2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4091029-A | RESOLVING AGENT FOR RACEMIC MIXTURES | ELI LILLY AND COMPANY (US) | 1978-05-23 | — | — | US | disclosed |
| US-3972925-A | RESOLUTION AGENT | ELI LILLY AND COMPANY (US) | 1976-08-03 | — | — | US | disclosed |