SCHEMBL116465

SCHEMBL116465

Nc1ccc(-c2ccc(N)cc2-c2ccccc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.61
TDP1 Q9NUW8 3/20 0.61
HSD17B10 Q99714 3/20 0.61
TAAR1 Q96RJ0 1/20 0.61
ALDH1A1 P00352 7/20 0.48
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
HPGD P15428 4/20 0.48
MAPT P10636 3/20 0.48
NPC1 O15118 5/20 0.48
RAB9A P51151 4/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
TP53 P04637 2/20 0.48
TSHR P16473 2/20 0.48
MAPK1 P28482 1/20 0.48
MAOA P21397 1/20 0.48
PTPRC P08575 2/20 0.47
LMNA P02545 2/20 0.47
NCOA1 Q15788 2/20 0.47
APAF1 O14727 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL650894 1.00 CYP3A4 (0.61) CYP3A4TDP1HSD17B10TAAR1ALDH1A1
SCHEMBL29372308 1.00 CYP3A4 (0.61) CYP3A4TDP1HSD17B10TAAR1ALDH1A1
SCHEMBL5459730 0.98 CYP3A4 (0.65) CYP3A4TDP1HSD17B10TAAR1ALDH1A1
SCHEMBL30670342 0.98 CYP3A4 (0.65) CYP3A4TDP1HSD17B10TAAR1ALDH1A1
SCHEMBL29458681 0.98 CYP3A4 (0.65) CYP3A4TDP1HSD17B10TAAR1ALDH1A1
Water SCHEMBL25433491 0.98 CYP3A4 (0.58) CYP3A4TDP1HSD17B10TAAR1ALDH1A1
SCHEMBL21582646 0.95 HSD17B10 (0.61) CYP3A4TDP1HSD17B10TAAR1ALDH1A1
SCHEMBL29830590 0.95 HSD17B10 (0.61) CYP3A4TDP1HSD17B10TAAR1ALDH1A1
SCHEMBL25301803 0.95 HSD17B10 (0.61) CYP3A4TDP1HSD17B10TAAR1ALDH1A1
SCHEMBL29658028 0.95 HSD17B10 (0.61) CYP3A4TDP1HSD17B10TAAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2814 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114284436-B Organic-inorganic hybrid short-wave infrared photoelectric detector, array formed by same and related preparation method 广州光达创新科技有限公司 2024-07-09 CN claimed
WO-2024139481-A1 LIGHT-EMITTING DEVICE, PREPARATION METHOD AND DISPLAY APPARATUS 广东聚华新型显示研究院 2024-07-04 WO claimed
WO-2024139488-A1 COMPOSITE MATERIAL AND PREPARATION METHOD THEREFOR, AND LIGHT-EMITTING DEVICE TCL科技集团股份有限公司 2024-07-04 WO claimed
CN-118284269-A Photoelectric device, preparation method thereof and display device TCL科技集团股份有限公司 2024-07-02 CN claimed
CN-118270734-A Composite material, preparation method thereof, light-emitting device and display device TCL科技集团股份有限公司 2024-07-02 CN claimed
CN-118284114-A Electroluminescent device and preparation method thereof TCL科技集团股份有限公司 2024-07-02 CN claimed
CN-118284270-A Test device, inkjet printing method and inkjet printing system 广东聚华印刷显示技术有限公司 2024-07-02 CN claimed
CN-118271769-A Composite material, preparation method thereof, photoelectric device and display device TCL科技集团股份有限公司 2024-07-02 CN claimed
CN-118284077-A Light-emitting device, preparation method thereof and display device TCL科技集团股份有限公司 2024-07-02 CN claimed
CN-118272088-A Composite material, preparation method thereof, photoelectric device and display device TCL科技集团股份有限公司 2024-07-02 CN claimed
WO-2000075731-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR CONTAINING SIMPLE QUINONES TO IMPROVE ELECTRICAL PROPERTIES LEXMARK INTERNATIONAL, INC. (US) 2000-12-14 WO claimed
EP-0577245-B1 Photogenerating azo pigments XEROX CORP (US) 1998-12-02 EP claimed
US-5747122-A ELECTRODES HAVE POLYIMIDE ALIGNING FILMS ON INNER SURFACES NIPPONDENSO CO., LTD. (JP) 1998-05-05 US claimed
US-5310862-A Photosensitive polyimide precursor compositions and process for preparing same TORAY INDUSTRIES, INC. (JP) 1994-05-10 US claimed
US-5281503-A Multilayer element with disazo pigments and charge generating layer XEROX CORPORATION (US) 1994-01-25 US claimed
EP-0577245-A1 Photogenerating azo pigments XEROX CORPORATION (US) 1994-01-05 EP claimed
EP-0160302-B1 FERROELECTRIC LIQUID CRYSTAL CELL HITACHI, LTD. (JP) 1993-07-21 EP claimed
EP-0301901-A2 Organic laminated photosensitive material of positive charging type MITA INDUSTRIAL CO. LTD. (JP) 1989-02-01 EP claimed
EP-0160302-A2 Ferroelectric liquid crystal cell HITACHI, LTD. (JP) 1985-11-06 EP claimed
US-4381886-A HYDRAZIDE-IMIDE COPOLYMER HITACHI, LTD. (JP) 1983-05-03 US claimed