SCHEMBL650894

SCHEMBL650894

Nc1ccc(-c2cc(N)ccc2-c2ccccc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.61
TDP1 Q9NUW8 3/20 0.61
HSD17B10 Q99714 3/20 0.61
TAAR1 Q96RJ0 1/20 0.61
ALDH1A1 P00352 7/20 0.48
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
HPGD P15428 4/20 0.48
MAPT P10636 3/20 0.48
NPC1 O15118 5/20 0.48
RAB9A P51151 4/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
TP53 P04637 2/20 0.48
TSHR P16473 2/20 0.48
MAPK1 P28482 1/20 0.48
MAOA P21397 1/20 0.48
PTPRC P08575 2/20 0.47
LMNA P02545 2/20 0.47
NCOA1 Q15788 2/20 0.47
APAF1 O14727 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL116465 1.00 CYP3A4 (0.61) CYP3A4TDP1HSD17B10TAAR1ALDH1A1
SCHEMBL29372308 1.00 CYP3A4 (0.61) CYP3A4TDP1HSD17B10TAAR1ALDH1A1
SCHEMBL5459730 0.98 CYP3A4 (0.65) CYP3A4TDP1HSD17B10TAAR1ALDH1A1
SCHEMBL30670342 0.98 CYP3A4 (0.65) CYP3A4TDP1HSD17B10TAAR1ALDH1A1
SCHEMBL29458681 0.98 CYP3A4 (0.65) CYP3A4TDP1HSD17B10TAAR1ALDH1A1
Water SCHEMBL25433491 0.98 CYP3A4 (0.58) CYP3A4TDP1HSD17B10TAAR1ALDH1A1
SCHEMBL21582646 0.95 HSD17B10 (0.61) CYP3A4TDP1HSD17B10TAAR1ALDH1A1
SCHEMBL29830590 0.95 HSD17B10 (0.61) CYP3A4TDP1HSD17B10TAAR1ALDH1A1
SCHEMBL25301803 0.95 HSD17B10 (0.61) CYP3A4TDP1HSD17B10TAAR1ALDH1A1
SCHEMBL29658028 0.95 HSD17B10 (0.61) CYP3A4TDP1HSD17B10TAAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116271976-A Enrichment method and detection method for advanced glycosylation end products 中国烟草总公司郑州烟草研究院 2023-06-23 CN claimed
US-7459047-B2 Preparation of flexible copper foil/polyimide laminate SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-12-02 US claimed
US-5976710-A HIGH DENSITY SEMICONDUCTORS; LOW THERMAL COEFFICIENT OF EXPANSION INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1999-11-02 US claimed
US-5601905-A Laminate for insulation protection of circuit boards NIPPON STEEL CHEMICAL CO., LTD. (JP) 1997-02-11 US claimed
US-5115090-A Polyamic acids and polyimides for multilayer elements, imsulators and passivation layers INTERNATIONAL BUSINESS MACHINES CORPORATION 1992-05-19 US claimed
US-4278326-A Liquid crystal display element HITACHI, LTD. (JP) 1981-07-14 US claimed
JP-57114258-A None JP disclosed
US-20250109265-A1 CLADS HAVING POLYMER FILMS AND METAL LAYERS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2025-04-03 US disclosed
US-20240336801-A1 ELECTRICALLY INSULATED WIRES AND CABLES U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-10-10 US disclosed
WO-2024180687-A1 POLYIMIDE POWDER FOR MOLDED BODY, AND POLYIMIDE MOLDED BODY UBE株式会社 2024-09-06 WO disclosed
US-20240052104-A1 DICARBONYL HALIDES, POLYMER COMPOSITIONS AND FILMS MADE THEREFROM U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-02-15 US disclosed
CN-116271976-A Enrichment method and detection method for advanced glycosylation end products 中国烟草总公司郑州烟草研究院 2023-06-23 CN disclosed
US-20230183435-A1 POLYIMIDE FILMS AND ELECTRONIC DEVICES DUPONT ELECTRONCS INC (US) 2023-06-15 US disclosed
EP-0286829-A2 Electronic device comprising a polyimide layer, and method for its production HITACHI, LTD. (JP) 1988-10-19 EP disclosed
US-4760126-A Fluorine-containing polyamide-acid derivative and polyimide HITACHI, LTD. (JP) 1988-07-26 US disclosed
US-4690999-A MOLECULARLY-ORIENTED POLYIMIDES BASED ON PARA-AROMATIC DIAMINES; FILMS; PROTECTIVE COATINGS; INTEGRATED CIRCUITS HITACHI, LTD. (JP) 1987-09-01 US disclosed
EP-0142149-A2 Use of fluorine containing polyimides for aligning layers of liquid crystal display devices. HITACHI, LTD. (JP) 1985-05-22 EP disclosed
EP-0133533-A2 Low thermal expansion resin material for a wiring insulating film. HITACHI, LTD. (JP) 1985-02-27 EP disclosed
JP-S57114258-A SEMICONDUCTOR DEVICE HITACHI LTD 1982-07-16 JP disclosed
US-4278326-A Liquid crystal display element HITACHI, LTD. (JP) 1981-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240052104-A1 DICARBONYL HALIDES, POLYMER COMPOSITIONS AND FILMS MADE THEREFROM PUF60, PICALM, PARG CYP3A4 3952/4885TDP1 2257/4885HSD17B10 3327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.