Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1164257 | 0.79 | TSHR (0.35) | KDM4EMAPTHTTHSD17B10TSHR | |
| SCHEMBL1164306 | 0.79 | TSHR (0.35) | KDM4EMAPTHSD17B10TSHR | |
| SCHEMBL4777219 | 0.78 | KDM4E (0.38) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL12878267 | 0.76 | MAPT (0.49) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL5373030 | 0.76 | KDM4E (0.39) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL5361361 | 0.76 | KDM4E (0.39) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL4775600 | 0.76 | KDM4E (0.39) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL16596446 | 0.75 | MAPT (0.43) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL12878322 | 0.75 | MAPT (0.51) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL12913178 | 0.74 | KDM4E (0.44) | ALDH1A1KDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011020712-A2 | OLIGOTHIOPHENES DERIVATIVES | UNIVERSITE LIBRE DE BRUXELLES (BE) | 2011-02-24 | — | — | WO | disclosed |