SCHEMBL5373030

SCHEMBL5373030

CCCCCCc1sc(-c2cccs2)c(-c2cccs2)c1CCCCCC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.39
ALDH1A1 P00352 6/20 0.39
GAA P10253 2/20 0.39
GPR35 Q9HC97 1/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
HPGD P15428 4/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
MAPT P10636 3/20 0.34
POLB P06746 2/20 0.34
ALOX15 P16050 2/20 0.34
HSD17B10 Q99714 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
STAT6 P42226 1/20 0.34
HTT P42858 1/20 0.34
HIF1A Q16665 1/20 0.34
GAPDH P04406 1/20 0.34
NR4A1 P22736 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4775600 1.00 KDM4E (0.39) KDM4EALDH1A1GAAGPR35NPC1
SCHEMBL5361361 1.00 KDM4E (0.39) KDM4EALDH1A1GAAGPR35NPC1
SCHEMBL1231111 0.96 KDM4E (0.37) KDM4EALDH1A1GAAGPR35NPC1
SCHEMBL4777219 0.89 KDM4E (0.38) KDM4EALDH1A1GAANPC1RAB9A
SCHEMBL4219592 0.87 KDM4E (0.32) KDM4EALDH1A1GAA
SCHEMBL12913178 0.82 KDM4E (0.44) KDM4EALDH1A1GAAGPR35NPC1
SCHEMBL5715244 0.82 KDM4E (0.44) KDM4EALDH1A1GAAGPR35NPC1
SCHEMBL30331131 0.81 KDM4E (0.36) KDM4EALDH1A1GAANPC1RAB9A
SCHEMBL1470712 0.80 KDM4E (0.42) KDM4EALDH1A1GAAGPR35NPC1
SCHEMBL2762298 0.78 KDM4E (0.36) KDM4EALDH1A1GAAGPR35HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6444808-B1 None US disclosed
US-7256064-B2 Organic semiconductor device DAI NIPPON PRINTING CO. LTD. (JP) 2007-08-14 US disclosed
US-20060138701-A1 Method and device for structuring organic layers POLYIC GMBH & CO. KG (DE) 2006-06-29 US disclosed
US-20060054883-A1 Organic semiconductor device DAI NIPPON PRINTING CO., LTD. (JP) 2006-03-16 US disclosed
US-6906189-B2 Catalysts and methods for catalytic oxidation PROCTER & GAMBLE COMPANY (US) 2005-06-14 US disclosed
US-6444808-B2 USEFUL AS LIGANDS FOR METAL BINDING, FOR PREPARING TRANSITION METAL (MANGANESE AND IRON) CONTAINING OXIDATION CATALYST USEFUL IN LAUDRY DETERGENT COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2002-09-03 US disclosed