Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.72 |
| ▸ | MMP14 | P50281 | 2/20 | 0.72 |
| ▸ | CASP6 | P55212 | 2/20 | 0.72 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ATIC | P31939 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11646620 | 1.00 | NSD2 (0.72) | NSD2MMP14CASP6EGFRALDH1A1 | |
| SCHEMBL29407520 | 0.84 | NSD2 (1.00) | NSD2MMP14CASP6EGFRALDH1A1 | |
| SCHEMBL1472403 | 0.84 | NSD2 (1.00) | NSD2MMP14CASP6EGFRALDH1A1 | |
| SCHEMBL4926613 | 0.84 | NSD2 (1.00) | NSD2MMP14CASP6EGFRALDH1A1 | |
| SCHEMBL11653804 | 0.84 | NSD2 (0.58) | NSD2MMP14CASP6EGFRALDH1A1 | |
| SCHEMBL11653798 | 0.84 | NSD2 (0.58) | NSD2MMP14CASP6EGFRALDH1A1 | |
| SCHEMBL11760061 | 0.83 | NSD2 (0.97) | NSD2MMP14CASP6EGFRALDH1A1 | |
| SCHEMBL2433663 | 0.80 | NSD2 (0.54) | NSD2MMP14CASP6EGFRALDH1A1 | |
| SCHEMBL112102 | 0.80 | EGFR (0.69) | NSD2MMP14CASP6EGFRALDH1A1 | |
| SCHEMBL29378452 | 0.80 | EGFR (0.69) | NSD2MMP14CASP6EGFRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29585-E | DYEING WOOL | CIBA-GEIGY CORPORATION (US) | 1978-03-21 | — | — | US | disclosed |
| US-3971738-A | Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component | CIBA-GEIGY AG (CH) | 1976-07-27 | — | — | US | disclosed |
| US-3933785-A | Azo compounds | CIBA-GEIGY AG (CH) | 1976-01-20 | — | — | US | disclosed |