Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.76 |
| ▸ | PGR | P06401 | 7/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.76 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.76 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.76 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.76 |
| ▸ | USP2 | O75604 | 2/20 | 0.76 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.76 |
| ▸ | THRB | P10828 | 1/20 | 0.76 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.76 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 7/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11647162 | 1.00 | AR (0.76) | ARPGRCYP3A4NR3C1SMN1; SMN2 | |
| SCHEMBL11645844 | 0.90 | AR (0.75) | ARPGRCYP3A4NR3C1SMN1; SMN2 | |
| SCHEMBL11645841 | 0.90 | AR (0.75) | ARPGRCYP3A4NR3C1SMN1; SMN2 | |
| Chlormadinone Acetate SCHEMBL40360 | 0.87 | AR (1.00) | ARPGRCYP3A4NR3C1SMN1; SMN2 | |
| Chlormadinone Acetate SCHEMBL11795531 | 0.87 | AR (1.00) | ARPGRCYP3A4NR3C1SMN1; SMN2 | |
| Chlormadinone Acetate SCHEMBL4948575 | 0.87 | AR (1.00) | ARPGRCYP3A4NR3C1SMN1; SMN2 | |
| Chlormadinone Acetate SCHEMBL29430402 | 0.87 | AR (1.00) | ARPGRCYP3A4NR3C1SMN1; SMN2 | |
| Chlormadinone Acetate SCHEMBL1460594 | 0.87 | AR (1.00) | ARPGRCYP3A4NR3C1SMN1; SMN2 | |
| Chlormadinone Acetate SCHEMBL15046 | 0.87 | AR (1.00) | ARPGRCYP3A4NR3C1SMN1; SMN2 | |
| Chlormadinone Acetate SCHEMBL1460593 | 0.87 | AR (1.00) | ARPGRCYP3A4NR3C1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4073900-A | DEHALOGENATION, PROGESTATIONAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DT) | 1978-02-14 | — | — | US | disclosed |